Copyright © Philip M. Parker, INSEAD. Terms of Use.

Definition: Peptide Bond |
Peptide BondNoun1. The primary linkage of all protein structures; the chemical bond between the carboxyl groups and amino groups that unites a peptide. Source: WordNet 1.7.1 Copyright © 2001 by Princeton University. All rights reserved. |
| Domain | Definitions |
Medicine | A covalent bond formed between the NH2 group of one amino acid and the COOH group of another(-NH-CO-), with the elimination of water. Source: European Union. (references) |
Source: compiled by the editor from various references; see credits. | |
(From Wikipedia, the free Encyclopedia)
A peptide bond is a chemical bond formed between two molecules when the carboxy group of one molecule reacts with the amino group of the other molecule, releasing a molecule of water (H2O). This is a dehydration synthesis reaction, and usually occurs between amino acids.

The resulting C-N bond is called a peptide bond, and the resulting molecule is called an amide. Polypeptides and proteins are chains of amino acids held together by peptide bonds. The backbone of PNA is also held together by peptide bonds.
The C-N bond has a partial double bond character (with the Nitrogen atom attaining a partial positive charge and the oxygen atom a partial negative charge) and the molecule can normally not rotate around this bond. The whole arrangement of the four C,O,N,H atoms as well as the two attached carbons in a peptide bond is planar.
A peptide bond can be broken by amide hydrolysis (the adding of water). The peptide bonds in proteins are metastable, meaning that in the presence of water they will break spontaneously, releasing about 10 kJ/mol of free energy, but this process is extremely slow. In living organisms, the process is facilitated by enzymes. Living organisms also employ enzymes to form peptide bonds; this process requires free energy.
Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Peptide bond."
Synonym: Peptide BondSynonym: peptide linkage (n). (additional references) |
Crosswords: Peptide Bond |
| English words defined with "peptide bond": peptide linkage. (references) |
| Specialty definitions using "peptide bond": Codon, Terminator ♦ Factor IXa ♦ Pepsin A, Protein Processing, Post-Translational. (references) |
| Domain | Title |
Books | |
Source: compiled by the editor from various references; see credits. | |
| Language | Translations for "peptide bond"; alternative meanings/domain in parentheses. | ||||||||||||||||||||||
Danish | peptidbinding (peptide bonding). (various references) | ||||||||||||||||||||||
Dutch | peptidebinding (peptide bonding). (various references) | ||||||||||||||||||||||
Finnish | peptidisidos (peptide bonding). (various references) | ||||||||||||||||||||||
French | liaison peptidique (peptide bonding). (various references) | ||||||||||||||||||||||
German | Peptidbindung (peptide bonding). (various references) | ||||||||||||||||||||||
Greek | πεπτιδικός δεσμός (peptide bonding). (various references) | ||||||||||||||||||||||
Italian | legame peptidico (peptide bonding). (various references) | ||||||||||||||||||||||
Japanese Kanji | ペプチド結合 (pelican, peptone, peril point, periscope, Peru). (various references) | ||||||||||||||||||||||
Japanese Katakana | ペプチドけつ"う. (various references) | ||||||||||||||||||||||
Pig Latin | eptidepay ondbay ligação peptídica (peptide bonding), formação de ligação peptídica (peptide bonding). (various references) enlace peptídico (peptide bonding). (various references) peptidbindning (peptide bonding). (various references) | ||||||||||||||||||||||
Scrabble® Enable2K-Verified Anagrams | |
| Words within the letters "b-d-d-e-e-i-n-o-p-p-t" | |
-3 letters: indebted, obedient. | |
-4 letters: betided, debited, deboned, denoted, dentoid, deponed, ebonite, endited, epidote, epitope, pentode, peptide, peptone, poinded, pointed. | |
-5 letters: bended, betide, bidden, bodied, bonded, bopeep, bopped, debone, denied, denote, dented, depend, depone, dieted, dinted, dipnet, dipped, doited, edited, endite, indeed, nipped, opened, opined, peined, pended, peptid, podite, pointe, ponded, ponied, poteen, potpie, tended. | |
| Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro. | |
Hexadecimal (or equivalents, 770AD-1900s) (references)50 65 70 74 69 64 65      42 6F 6E 64 |
| Leonardo da Vinci (1452-1519; backwards) (references)
|
Binary Code (1918-1938, probably earlier) (references)01010000 01100101 01110000 01110100 01101001 01100100 01100101 00100000 01000010 01101111 01101110 01100100 |
HTML Code (1990) (references)P e p t i d e   B o n d |
ISO 10646 (1991-1993) (references)0050 0065 0070 0074 0069 0064 0065      0042 006F 006E 0064 |
Encryption (beginner's substitution cypher): (references)50718286757071236818070 |
| 1. Definition 2. Synonyms 3. Crosswords 4. Usage: Commercial | 5. Translations: Modern 6. Anagrams 7. Orthography 8. Bibliography |
Copyright © Philip M. Parker, INSEAD. Terms of Use.