Webster's Online Dictionary
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Specialty Expressions: IMMUNOGLOBULIN IDIOTYPES

ExpressionsDomainDefinition
Immunoglobulin IdiotypesHealthUnique, genetically controlled determinants present on antibodies whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the variable regions of both immunoglobin polypeptide chains. (references)

Source: compiled by the editor from various references; see credits.

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