Webster's Online Dictionary
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Specialty Expressions: I-KAPPA B

ExpressionsDomainDefinition
I-kappa BHealthFamily of inhibitory proteins which bind to the rel family of transcription factors and modulate their activity. The transcription factor NF-kappa B is generally present in an inactive cytoplasmic form, bound to inhibitory IkB proteins. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus. (references)

Source: compiled by the editor from various references; see credits.

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