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Date "HOLOPHERNES" was first used in popular English literature: sometime before 1862. (references)

Specialty Definition: HOLOPHERNES

DomainDefinition
Literature1: Holofernes, in Love's Labour's Lost. Shakespeare satirises in this character the literary affectations of the Lyly school. An anagram of Johnes Florio.
2: Holophernes (4 syl.). Master Tubal Holophernes. The great sophister-doctor, who, in the course of five years and three months, taught Gargantua to say his A B C backward. (Rabelais: Gargantua, book i. 14.). Source: Brewer's Dictionary.

Source: compiled by the editor from various references; see credits.

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