| Webster's Online Dictionary |
| Expressions | Domain | Definition | |
| Factor VIIIa | Health | Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similar in structure and generation to factor Va. (references) | |
Source: compiled by the editor from various references; see credits. | Top | ||
