Ethionine
| Ethionine | |
|---|---|
 |
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| IUPAC name | 2-Amino-4-ethylsulfanylbutyric acid |
| Other names | S-Ethyl-L-homocysteine |
| Identifiers | |
| CAS number | [13073-35-3] |
| PubChem | |
| SMILES |
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| Properties | |
| Molecular formula | C6H13NO2S |
| Molar mass | 163.239 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Ethionine is a non-proteinogenic amino acid structurally related to methionine, with an ethyl group in place of the methyl group.
Ethionine is an antimetabolite and methionine antagonist. It prevents amino acid incorporation into proteins and interferes with cellular use of adenosine triphosphate (ATP). Because of these pharmacological effects, ethionine is highly toxic and is a potent carcinogen.[1]
References
- Narayan Shivapurkar, Mary J. Wilson and Lionel A. Poirier (1984). "Hypomethylation of DNA in ethionine-fed rats". Carcinogensis 5 (8): 989–992. doi:. PMID 6744518.
External links
Source: adapted by the editor from Wikipedia, the free encyclopedia; from the article "Ethionine". Image Credit.
