| Webster's Online Dictionary |
| Domain | Definition | ||
| Health | A trypanocidal agent and possible antiviral agent that is widely used in experimental cell biology and biochemistry. Ethidium has several experimentally useful properties including binding to nucleic acids, noncompetitive inhibition of nicotinic acetylcholine receptors, and fluorescence among others. It is most commonly used as the bromide. (references) | ||
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Source: compiled by the editor from various references; see credits. | Top | ||
| Expressions | Definition | ||
| Ethidium bromide | Ethidium bromide (EtBr) is an intercalating agent commonly used as a nucleic acid stain in molecular biology laboratories for techniques such as agarose gel electrophoresis. When exposed to ultraviolet light, it will fluoresce with a red-orange color, especially after binding to DNA (almost 20-fold increase). This is likely not due to rigid stabilization of the phenyl moiety, because the phenyl ring has been shown to project outside the intercalated bases. The increased hydrophobicity of the environment is believed to be responsible. Because it binds to DNA, ethidium bromide is a very strong mutagen, and may possibly be a carcinogen or teratogen. Important hazard information follows. As with most fluorescent compounds, it is aromatic. The main portion of the molecule is a tricyclic structure with aniline (amino-benzene) groups on either side of a pyridine (six-atom, nitrogen-containing, aromatic ring). The dibenzopyridine structure is known as a phenanthridine. (references) | ||
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Source: compiled by the editor from various references; see credits. | Top | ||
| Expressions | Domain | Definition | |
| Ethidium bromide | Geology | A fluorescent dye used to stain DNA and RNA. The dye fluoresces when exposed to UV light. (references) | |
| Ethidium bromide | Medicine | A DNA-binding molecule used for detecting DNA strands under the action of UV-rays. Source: European Union. (references) | |
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Source: compiled by the editor from various references; see credits. | Top | ||
Topics by Level of Interest: ETHIDIUM | ||||
| Topics sorted by level of Interest | Level (1=low, 600=high) | Topics sorted Alphabetically | Level (1=low, 600=high) | |
| Ethidium bromide | 21 | Ethidium bromide | 21 | |
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Source: the editor, created by/for EVE to gauge likely levels of human interest in linguistically triggered topics (compiled across various sources, such as Wikipedia and specialty expression glosses). | ||||
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