Benzamide
| Benzamide | |
|---|---|
 | |
| IUPAC name | Benzamide |
| Other names | Benzoic acid amide, Phenyl carboxamide, Benzoylamide |
| Identifiers | |
| CAS number | [55-21-0] |
| PubChem | |
| EINECS number | |
| RTECS number | CU8700000 |
| SMILES | C1=CC=C(C=C1)C(=O)N |
| InChI | 1/C7H7NO/c8-7(9)6-4-2-1- 3-5-6/h1-5H,(H2,8,9)/f/h8H2 |
| Properties | |
| Molecular formula | C7H7NO |
| Molar mass | 121.14 g/mol |
| Appearance | Off-white solid |
| Density | 1.341 g/cm3 |
| Melting point |
127 - 130 °C |
| Boiling point |
288 °C |
| Solubility in water | 13 g/l pKa in DMSO = 23.35 |
| Hazards | |
| EU classification | Harmful (Xn) |
| NFPA 704 |
 1
1
0
|
| R-phrases | R22, R40 |
| S-phrases | S36/37/39 |
| Flash point | 180 °C |
| Autoignition temperature |
> 500 °C |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references | |
Benzamide is an off-white solid with the chemical formula of C6H5CONH2. It is a derivative of benzoic acid. It is slightly soluble in water, and soluble in many organic solvents.
Benzamides
Amisulpride - a substituted benzamide
Benzamides are a class of amides of benzoic acid. In psychiatry some substituted benzamides are therapeutically used as neuroleptics and/or antipsychotics. Two active substances from the group of benzamides are in use:
- Sulpiride
- Amisulpride
Another benzamide, Remoxipride, was taken off the market in 1993 because of life-threatening side effects. Some analgetics like salicylamide or ethenzamide also have benzamide structures.
See also
- ATC code N05#N05AL Benzamides
External links
- Physical characteristics
- Safety MSDS data
- 1309016066 at GPnotebook
Source: adapted by the editor from Wikipedia, the free encyclopedia; from the article "Benzamide". Image Credit.
