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ACETYLCHOLINE RECEPTOR

Specialty Definition: ACETYLCHOLINE RECEPTOR

DomainDefinition

Medicine

Receptor specifically sensitive to acetylcholine. Cholinoceptors are of two main subtypes:muscarinic and nicotinic cholinoceptors. Source: European Union. (references)

Source: compiled by the editor from various references; see credits.

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Specialty Definition: Acetylcholine receptor

(From Wikipedia, the free Encyclopedia)

An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of the neurotransmitter acetylcholine by opening a pathway in the membrane for the diffusion of ions across the cell membrane. Like other transmembrane receptors, acetylcholine receptors are classified according to their "pharmacology," or according to their relative affinities and sensitivities to different molecules. Although all acetylcholine receptors, by definition, respond to acetylcholine, they respond to other molecules as well. Generally nicotinic AChRs respond more rapidly to acetylcholine and are therefore found in muscle and brain tissues, whereas muscarinic receptors activate slowly in the presence of acetylcholine and are found mainly in the parasympathetic part of the autonomic nervous system.

Molecular biology has shown that the nicotinic and muscarinic receptors belong to distinct protein superfamilies. The nAChr is an ion channel, and like other members of the ligand-gated ion channel superfamily, is composed of five protein subunits arranged like staves around a barrel. The subunit composition is highly variable across different tissues. In contrast, the mAChR is not itself an ion channel, but belongs to the superfamily of G-protein coupled receptors. It activates ionic currents by initiating a second messenger cascade.

Muscarinic acetylcholine receptors can be blocked by the drugs atropine and scopolamine.

Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Acetylcholine receptor."

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Commercial Usage: ACETYLCHOLINE RECEPTOR

DomainTitle

Books

  • Nicotinoid Insecticides and the Nicotinic Acetylcholine Receptor (reference)

    (more book examples)

Source: compiled by the editor from various references; see credits.

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Non-Fiction Usage: ACETYLCHOLINE RECEPTOR

SubjectTopicQuote

Health

A special blood test can detect the presence of immune molecules or acetylcholine receptor antibodies. (references)

These are not autoimmune disorders, but are caused by defective genes that control proteins in the acetylcholine receptor or in acetylcholineterase. (references)

Scientists believe the thymus gland may give incorrect instructions about the production of the acetylcholine receptor antibodies, thereby setting the stage for the attack on neuromuscular transmission. (references)

Source: compiled by the editor from ICON Group International, Inc.; see credits.

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Frequency of Internet Keywords: ACETYLCHOLINE RECEPTOR

The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com.
 
ExpressionFrequency
per Day

acetylcholine receptor

7
Source: compiled by the editor from various references; see credits.

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Modern Translation: ACETYLCHOLINE RECEPTOR

Language Translations for "ACETYLCHOLINE RECEPTOR"; alternative meanings/domain in parentheses.

Danish

  

kolinerg receptor (cholinergic receptor, cholinoceptor, Receptor specifically sensitive to acetylcholine.Cholinoceptors are of two main subtypes:muscarinic and nicotinic cholinoceptors.). (various references)

   

Dutch

  

cholinerge receptor (cholinergic receptor, cholinoceptor, Receptor specifically sensitive to acetylcholine.Cholinoceptors are of two main subtypes:muscarinic and nicotinic cholinoceptors.). (various references)

   

Finnish

  

koliinireseptori (cholinergic receptor, cholinoceptor, Receptor specifically sensitive to acetylcholine.Cholinoceptors are of two main subtypes:muscarinic and nicotinic cholinoceptors.). (various references)

   

French

  

récepteur cholinergique (Receptor specifically sensitive to acetylcholine.Cholinoceptors are of two main subtypes:muscarinic and nicotinic cholinoceptors.). (various references)

   

German

  

cholinergischer Rezeptor (cholinergic receptor, cholinoceptor, Receptor specifically sensitive to acetylcholine.Cholinoceptors are of two main subtypes:muscarinic and nicotinic cholinoceptors.), cholinergischer Neurotransmitter-spezifischer Rezeptor (cholinergic receptor, cholinoceptor, Receptor specifically sensitive to acetylcholine.Cholinoceptors are of two main subtypes:muscarinic and nicotinic cholinoceptors.). (various references)

   

Greek 

  

χολινεργικός υποδοχέας (cholinergic receptor, cholinoceptor, Receptor specifically sensitive to acetylcholine.Cholinoceptors are of two main subtypes:muscarinic and nicotinic cholinoceptors.). (various references)

   

Italian

  

recettore per l'acetilcolina (cholinergic receptor, cholinoceptor, Receptor specifically sensitive to acetylcholine.Cholinoceptors are of two main subtypes:muscarinic and nicotinic cholinoceptors.), recettore colinergico (cholinergic receptor, cholinoceptor, Receptor specifically sensitive to acetylcholine.Cholinoceptors are of two main subtypes:muscarinic and nicotinic cholinoceptors.). (various references)

   

Pig Latin

  

acetylcholineay eceptorray

   

Portuguese

  

receptor colinérgico (cholinergic receptor, cholinoceptor, Receptor specifically sensitive to acetylcholine.Cholinoceptors are of two main subtypes:muscarinic and nicotinic cholinoceptors.). (various references)

   

Spanish

  

receptor colinérgico (cholinergic receptor, cholinoceptor, Receptor specifically sensitive to acetylcholine.Cholinoceptors are of two main subtypes:muscarinic and nicotinic cholinoceptors.). (various references)

   

Swedish

  

kolinerg receptor (cholinergic receptor, cholinoceptor, Receptor specifically sensitive to acetylcholine.Cholinoceptors are of two main subtypes:muscarinic and nicotinic cholinoceptors.). (various references)

Source: compiled by the editor from various translation references.

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Anagrams: ACETYLCHOLINE RECEPTOR

Scrabble® Enable2K-Verified Anagrams

Words within the letters "a-c-c-c-e-e-e-e-h-i-l-l-n-o-o-p-r-r-t-t-y"

-4 letters: chlortetracycline.

Source: compiled by the editor from various references; see credits.

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INDEX

1. Usage: Commercial
2. Quotations: Non-fiction
3. Expressions: Internet
4. Translations: Modern
5. Anagrams
6. Bibliography


  

Copyright © Philip M. Parker, INSEAD. Terms of Use.